HEREDITARY DISEASE FOUNDATION
Annual Giving
$2.9M-21% YoY
Grants
16
Median Grant
$100K
Organizations Funded
15
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Foundation Overview
Mission
The Hereditary Disease Foundation funds innovative research to cure Huntington's disease and impact other brain disorders. HDF aims to cure genetic disorders, notably Huntington's disease, by supporting basic biomedical research.
Focus Areas
Grant Types
Funded Initiatives
2025 Transformative Research Award ($1 million to Dr. Christopher Pearson for CAG repeat contraction research); 2024 Transformative Research Award ($1 million); Postdoctoral Fellowships ($100,000 per year for two years); Research Grants ($100,000 one-year); HD Career Advancement Grants; Leslie Gehry Prize for Innovation in Science
How to Apply
Two-stage process: Letter of Intent (LOI) required first, then full application by invitation only. All applications submitted through ProposalCentral. Various deadlines: HD-CAG LOIs Jan 15-Feb 19, 2025; TRA LOIs Nov 14, 2025-Jan 15, 2026; Grant/PDF LOIs July 15-Sep 3, 2025.
Does Not Fund
Does not pay indirect costs/overhead; no salary support for collaborators; no research funding for HD-CAG program; exclusive use requirement; renewal limited to one additional year; required progress reports for continued funding eligibility
Based on publicly available information from the foundation's 990 filings and website.
Giving History
$2.9M
Grants
16
Median
$100K
States
5
$3.6M
Grants
16
Median
$75K
States
7
$1.3M
Grants
10
Median
$133K
States
2
Grant Size Distribution
$100K
Typical Grant (Median)
$30K
Smallest
$100K
25th Pctile
$182K
75th Pctile
$1.1M
Largest
Excludes grants ≤ $5K. Half fall between $100K and $182K.
Largest Recent Grants
$1.1M
2024
WASHINGTON UNIVERSITY SCHOOL OF MEDICINE IN ST LOUIS
MO · SCIENTIFIC RESEARCH
$200K
2024
Foreign Grants - CANADA
SCIENTIFIC RESEARCH
$200K
2024
NORTHWESTERN UNIVERSITY
IL · SCIENTIFIC RESEARCH
$200K
2024
Foreign Grants - AUSTRALIA
SCIENTIFIC RESEARCH
$176K
2024
THE BOARD OF TRUSTEES OF THE LELAND STANF
CA · SCIENTIFIC RESEARCH
Geographic Focus
Top states by total grant dollars. Based on IRS filing data.
Financial Overview
Grants paid shown as percentage of total assets
Data sourced from IRS 990 and 990-PF filings and publicly available foundation websites. Grant data, financial figures, and organizational details reflect historical filings and may not represent current operations or funding priorities. Verify directly with the foundation before applying. See an issue? Let us know.